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Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non

mer. févr. 26, 2020 5:34 pm

www.thelancet.com/haematology Vol 7 March 2020

The PROUD-PV and CONTINUATION-PV trials aimed to compare the novel monopegylated interferon ropeginterferon alfa-2b with hydroxyurea, the standard therapy for patients with polycythaemia vera, over 3 years of treatment.

« Implications of all the available evidence Taken together with pre-existing evidence, these findings suggest that ropeginterferon alfa-2b can be considered as first-line cytoreductive therapy instead of hydroxyurea and should therefore change treatment algorithms for polycythaemia vera »

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